To materialize, or activate, a suit, a disc (called a Creature Power Disc) with preprogrammed features and an actual DNA sample from the corresponding creature are needed. The most prominent are the Creature Power Suits, vests created by Aviva that allow a user to materialize a suit (called a Creature Power Suit or simply a Creature Power) that has a certain creature's characteristics and abilities, and sometimes its behavior. The Wild Kratts use futuristic and science fiction-like equipment on their adventures. The Wild Kratts also occasionally enlist children called 'Wild Kratts kids,' who help the Wild Kratts from their homes however they can.

While traveling around the world to learn all about the animals that inhabit it, the Wild Kratts perform 'creature rescues,' in which they save the animals from various dilemmas, which include getting caught with one of the show's recurring villains, who include rival inventor Zach Varmitech ( Zachary Bennett), fashion designer Donita Donata ( Eva Almos) and her henchman, Dabio ( Cory Doran), Chef Gourmand (Zachary Bennett), and Paisley Paver ( Julie Lemieux) and her henchman, Rex (Cory Doran) rebuilding habitats or if they are young, reuniting them with their families. Together, they are known as the Wild Kratts. Accompanying them on their adventures are fellow teammates Aviva Corcovado ( Athena Karkanis), an inventor Koki (Sabryn Rock), a computer expert and mechanic and Jimmy Z ( Jonathan Malen), an assistant and pilot of the Tortuga HQ, a turtle-shaped aircraft that serves as the their mobile headquarters. Wild Kratts centers on the Kratt brothers, Chris Kratt ( Chris Kratt) and Martin Kratt ( Martin Kratt), who travel around the world to learn all about the animals that inhabit it.

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